WZ222 - DNA纳米技术研究者

2025

Design of mismatch closure for enhanced specificity in DNA strand displacement reactions

Nucleic Acids Research 53 (13), gkaf660 (2025)

2025

Massively parallel homogeneous amplification of chip-scale DNA for DNA information storage (MPHAC-DIS)

Nature Communications 16 (1), 667 (2 citations)

2024

Random Sanitization in DNA information storage using CRISPR-Cas12a

Journal of the American Chemical Society 146 (51), 35155-35164 (4 citations)

2024

Selective Enrichment of Low‐Abundance DNA Variants Based on Programmable Peptide Nucleic Acid Probes

Chinese Journal of Chemistry 42 (21), 2572-2580 (2 citations)

2024

Design of enhanced entropy-driven non-covalent DNA catalytic reactions via the paired junction structure

Chemical Engineering Journal 498, 155509 (2 citations)

2024

Building a stable and robust anti-interference DNA dissipation system by eliminating the accumulation of systemic specified errors

Analytica Chimica Acta 1302, 342493 (2024)

2024

Extended Enrichment for Ultrasensitive Detection of Low‐Frequency Mutations by Long Blocker Displacement Amplification

Angewandte Chemie International Edition 63 (19), e202400551 (8 citations)

2024

Modified unit-mediated strand displacement reactions for direct detection of single nucleotide variants in active double-stranded DNA

ACS Nano 18 (19), 12401-12411 (10 citations)

2024

Movable toehold for leakless self-assembly circuits

Biosensors and Bioelectronics 245, 115823 (7 citations)

2023

A hairpin probe-mediated exponential amplification reaction for highly sensitive and specific detection of microRNAs

Chemical Communications 59 (28), 4158-4161 (6 citations)

2022

A PAM-free CRISPR/Cas12a ultra-specific activation mode based on toehold-mediated strand displacement and branch migration

Nucleic Acids Research 50 (20), 11727-11737 (57 citations)

2022

A Target-Feedback Rolling-Cleavage signal amplifier for ultrasensitive electrochemical detection of miRNA with Self-Assembled CeO2@ Ag hybrid nanoflowers

Bioelectrochemistry 146, 108152 (4 citations)

2022

Toehold-mediated nonenzymatic DNA strand displacement coupling UDG mediated PCR and multi-code magnetic beads for DNA genotyping

Microchemical Journal 178, 107340 (4 citations)

2022

Bulge-loop tuned entropy-driven catalytic reaction and tag-encoded barcodes for multiplexed mutation detection

Sensors and Actuators B: Chemical 358, 131462 (15 citations)

2022

Specific and robust hybridization based on double-stranded nucleic acids with single-base resolution

Analytica Chimica Acta 1199, 339568 (3 citations)

2022

Cooperative branch migration: a mechanism for flexible control of DNA strand displacement

ACS Nano 16 (2), 3135-3144 (32 citations)

2021

DNAzyme based three-way junction assay for antibody-free detection of locus-specific N6-methyladenosine modifications

Biosensors and Bioelectronics 194, 113625 (38 citations)

2021

Ultrasensitive electrochemical biosensor for attomolar level detection of let 7a based on toehold mediated strand displacement reaction circuits and molecular beacon mediated …

Analytica Chimica Acta 1147, 108-115 (19 citations)

2021

An integrated fluorescence biosensor for microRNA detection based on exponential amplification reaction-triggered three-dimensional bipedal DNA walkers

Analytica Chimica Acta 1143, 157-165 (33 citations)

2020

Simulation-guided DNAzyme based nanomachine design for identifying single nucleotide variants

Sensors and Actuators B: Chemical 324, 128719 (3 citations)

2020

Phage-guided targeting, discriminative imaging, and synergistic killing of bacteria by AIE bioconjugates

Journal of the American Chemical Society 142 (8), 3959-3969 (204 citations)

2020

Multiplex real-time PCR using double-strand primers and probes for the detection of nucleic acids

Analytical Methods 12 (44), 5392-5396 (2 citations)

探索DNA纳米技术的无限可能

研究方向

DNA数据存储

高通量DNA测序

核酸分子诊断

发表成果

Design of mismatch closure for enhanced specificity in DNA strand displacement reactions

Massively parallel homogeneous amplification of chip-scale DNA for DNA information storage (MPHAC-DIS)

Random Sanitization in DNA information storage using CRISPR-Cas12a

Selective Enrichment of Low‐Abundance DNA Variants Based on Programmable Peptide Nucleic Acid Probes

Design of enhanced entropy-driven non-covalent DNA catalytic reactions via the paired junction structure

Building a stable and robust anti-interference DNA dissipation system by eliminating the accumulation of systemic specified errors

Extended Enrichment for Ultrasensitive Detection of Low‐Frequency Mutations by Long Blocker Displacement Amplification

Modified unit-mediated strand displacement reactions for direct detection of single nucleotide variants in active double-stranded DNA

Movable toehold for leakless self-assembly circuits

A hairpin probe-mediated exponential amplification reaction for highly sensitive and specific detection of microRNAs

A PAM-free CRISPR/Cas12a ultra-specific activation mode based on toehold-mediated strand displacement and branch migration

A Target-Feedback Rolling-Cleavage signal amplifier for ultrasensitive electrochemical detection of miRNA with Self-Assembled CeO2@ Ag hybrid nanoflowers

Toehold-mediated nonenzymatic DNA strand displacement coupling UDG mediated PCR and multi-code magnetic beads for DNA genotyping

Bulge-loop tuned entropy-driven catalytic reaction and tag-encoded barcodes for multiplexed mutation detection

Specific and robust hybridization based on double-stranded nucleic acids with single-base resolution

Cooperative branch migration: a mechanism for flexible control of DNA strand displacement

DNAzyme based three-way junction assay for antibody-free detection of locus-specific N6-methyladenosine modifications

Ultrasensitive electrochemical biosensor for attomolar level detection of let 7a based on toehold mediated strand displacement reaction circuits and molecular beacon mediated …

An integrated fluorescence biosensor for microRNA detection based on exponential amplification reaction-triggered three-dimensional bipedal DNA walkers

Simulation-guided DNAzyme based nanomachine design for identifying single nucleotide variants

Phage-guided targeting, discriminative imaging, and synergistic killing of bacteria by AIE bioconjugates

Multiplex real-time PCR using double-strand primers and probes for the detection of nucleic acids

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